Core Framework & Diagram Can Autoimmunity Reverse?

Needs careful treatment. No dietary intervention has been proven by randomized controlled trials to independently reverse autoimmune disease. Dietary adjustment (like Mediterranean diet, reducing ultra-processed foods) benefits lowering inflammation and improving gut microbiome — can assist disease management, but can't replace drug treatment or 'eliminate' autoimmune memory. Claims that 'diet can cure XX disease' require checking evidence quality — such assertions typically lack randomized controlled trial support.

In some patients, under specific conditions, attempting drug reduction or stopping under specialist monitoring is feasible. But stopping medication on your own is dangerous. Relapse is often worse than before, and may cause irreparable organ damage. Any dose reduction plan must be carried out under close laboratory and clinical monitoring, with pre-established standards of 'if this indicator appears, immediately restart treatment.'

HSCT currently only applies to specific severe autoimmune disease patients who failed standard treatment. It's not an option for everyone; risk-benefit careful assessment at an experienced transplant center is required. If interested, consult a specialist; don't seek this treatment through irregular channels. Safety has improved significantly at professional centers with technological improvement, but careful evaluation is still needed.

Most autoimmune diseases themselves don't cause infertility, but some treatment drugs (like methotrexate, cyclophosphamide) have reproductive toxicity, requiring stopping at least three to six months before planning conception. Some autoimmune diseases (like SLE, antiphospholipid syndrome) increase pregnancy complication risk, requiring specialty monitoring. Pregnancy plans should be discussed in detail with rheumatology/immunology physicians to formulate an individualized plan.

Depression and anxiety rates in chronic autoimmune disease patients are significantly higher than the general population — not just 'bad mood'; direct physiological mechanisms are involved (chronic inflammatory factors directly affect the brain). Acknowledging this connection, seeking psychological support (counseling, support groups, medication treatment when necessary), is an important component of the treatment plan, not a sign of weakness. Many hospital rheumatology/immunology departments have begun integrating mental health evaluation into routine follow-up.